KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
29.7
Human Site:
Y419
Identified Species:
54.44
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
Y419
P
V
N
G
R
R
L
Y
K
D
F
V
L
N
V
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
V385
R
L
S
G
E
R
V
V
Y
S
V
Y
S
A
V
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
S380
F
N
N
V
L
R
L
S
G
E
R
V
V
Y
S
Dog
Lupus familis
XP_541867
872
95696
Y419
P
V
N
G
R
R
L
Y
K
D
F
V
L
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
Y419
P
V
N
G
R
R
L
Y
K
D
F
V
L
N
V
Rat
Rattus norvegicus
P31421
872
95755
Y419
P
V
N
G
R
R
L
Y
K
D
F
V
L
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
Y419
P
V
S
G
R
R
L
Y
R
D
F
M
L
N
V
Chicken
Gallus gallus
XP_416842
879
98936
Y431
H
L
D
G
K
K
L
Y
K
D
Y
L
L
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
Q417
C
Q
D
S
T
A
L
Q
P
W
E
L
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
W460
H
L
Q
S
E
S
V
W
Y
R
K
I
S
T
D
Honey Bee
Apis mellifera
NP_001011624
933
103448
Y461
N
Y
D
R
G
V
F
Y
K
N
Y
L
L
N
V
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
Y510
N
I
D
G
S
D
F
Y
Q
N
Y
L
L
K
V
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
F1002
P
I
D
G
R
K
L
F
K
E
Y
I
L
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
20
26.6
100
N.A.
100
100
N.A.
80
46.6
N.A.
13.3
N.A.
0
33.3
26.6
46.6
P-Site Similarity:
100
40
40
100
N.A.
100
100
N.A.
100
86.6
N.A.
26.6
N.A.
26.6
60
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
39
0
0
8
0
0
0
47
0
0
0
0
8
% D
% Glu:
0
0
0
0
16
0
0
0
0
16
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
16
8
0
0
39
0
0
0
0
% F
% Gly:
0
0
0
70
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
16
0
0
0
% I
% Lys:
0
0
0
0
8
16
0
0
54
0
8
0
0
16
0
% K
% Leu:
0
24
0
0
8
0
70
0
0
0
0
31
77
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
8
39
0
0
0
0
0
0
16
0
0
0
54
0
% N
% Pro:
47
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
8
8
0
0
0
0
0
8
% Q
% Arg:
8
0
0
8
47
54
0
0
8
8
8
0
0
8
0
% R
% Ser:
0
0
16
16
8
8
0
8
0
8
0
0
16
0
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
39
0
8
0
8
16
8
0
0
8
39
8
0
70
% V
% Trp:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
62
16
0
31
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _